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Protein Coding Gene : Papolb poly (A) polymerase beta (testis specific)
Primary Identifier  MGI:1932115 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  56522
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable poly(A) RNA polymerase activity. Predicted to be involved in RNA 3'-end processing and mRNA processing. Located in cytoplasm and nucleus. Is expressed in ductus deferens; epididymis; skin; and testis. Orthologous to human PAPOLB (poly(A) polymerase beta).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit male infertility associated with reduced testes weight, smaller seminiferous tubules, and arrested spermiogenesis. [provided by MGI curators]
  • synonyms:
  • poly (A) polymerase pseudogene,
  • MGI:109300,
  • TPAP,
  • Papt,
  • poly (A) polymerase, pseudogene,
  • MGI:1931138,
  • MGD-MRK-38345,
  • poly (A) polymerase beta (testis specific),
  • Papola-ps,
  • Papolb,
  • poly (A) polymerase alpha, pseudogene,
  • Plap-ps
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