| Primary Identifier | MGI:1352745 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 14086 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin filament binding activity. Involved in cell migration and positive regulation of filopodium assembly. Acts upstream of or within actin filament bundle assembly. Located in filopodium; growth cone; and lamellipodium. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human FSCN1 (fascin actin-bundling protein 1). PHENOTYPE: Mice homozygous for a gene trap allele show partial neonatal lethality, smaller size, enlarged lateral ventricles, abnormal anterior commissure pars posterior morphology, impaired migration of mature dendritic cells, and hypopigmentation due to migration and cell cycle defects in melanoblasts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
