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Protein Coding Gene : Usp42 ubiquitin specific peptidase 42
Primary Identifier  MGI:1924050 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  76800
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables cysteine-type deubiquitinase activity. Involved in protein deubiquitination. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain; eye; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human USP42 (ubiquitin specific peptidase 42).
PHENOTYPE: Mice homozygous for a null allele exhibit fecundity and behavioral abnormalities, hyperactivity, increased T cell number, abnormal lens morphology, and cataracts. Males display oligozoospermia and testis degeneration. [provided by MGI curators]
  • synonyms:
  • MGI:2444457,
  • A630018G05Rik,
  • D5Ertd591e,
  • 2410140K03Rik,
  • Usp42,
  • DNA segment, Chr 5, ERATO Doi 591, expressed,
  • ubiquitin specific peptidase 42,
  • MGI:1261892,
  • RIKEN cDNA A630018G05 gene,
  • RIKEN cDNA 2410140K03 gene,
  • MGI:1920429,
  • 3110031A07Rik,
  • RIKEN cDNA 3110031A07 gene
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