Primary Identifier | MGI:3036247 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 231876 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable myosin VI binding activity; protein phosphatase inhibitor activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including endosomal transport; protein phosphorylation; and transferrin transport. Predicted to act upstream of or within axon guidance and neurotrophin TRK receptor signaling pathway. Predicted to be located in several cellular components, including endosome; growth cone; and neuronal cell body. Is expressed in brain; olfactory cortex marginal layer; and pancreas. Orthologous to human LMTK2 (lemur tyrosine kinase 2). PHENOTYPE: Mice homozygous for a null mutation in this gene display partial prenatal lethality, male infertility, and azoospermia. [provided by MGI curators] |