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Protein Coding Gene : Tecpr1 tectonin beta-propeller repeat containing 1

Primary Identifier  MGI:1917631 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  70381
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in autophagosome maturation and regulation of autophagosome maturation. Predicted to be located in nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in autophagosome membrane and lysosomal membrane. Is expressed in several structures, including alimentary system; brain; cochlea; ganglia; and vibrissa follicle. Orthologous to human TECPR1 (tectonin beta-propeller repeat containing 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired selective autophagy and abnormal response to bacterial infection in MEFs. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2210010N04 gene,
  • mKIAA1358,
  • 2210010N04Rik,
  • Tecpr1,
  • tectonin beta-propeller repeat containing 1

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