| Primary Identifier | MGI:1347464 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 15228 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including neuron differentiation; positive regulation of neuroblast proliferation; and regulation of neuron differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; early embryo; embryo ectoderm; gonad; and sensory organ. Used to study Rett syndrome and congenital variant of Rett syndrome. Human ortholog(s) of this gene implicated in congenital variant of Rett syndrome. Orthologous to human FOXG1 (forkhead box G1). PHENOTYPE: Homozygous mutants exhibit dramatically reduced cerebral hemispheres, missing ventral telencephalic structures, impaired migration of efferent thalamocortical axons, and multiple eye defects. Mutants die at birth from respiratory failure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
