| Primary Identifier | MGI:105053 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 15505 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables alpha-tubulin binding activity. Acts upstream of or within several processes, including negative regulation of intracellular signal transduction; negative regulation of protein localization to mitochondrion; and positive regulation of protein tyrosine kinase activity. Located in cytoplasm and nucleus. Colocalizes with microtubule. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and limb. Orthologous to human HSPH1 (heat shock protein family H (Hsp110) member 1). PHENOTYPE: Homozygous inactivation of this gene leads to decreased susceptibility to ischemic brain injury. [provided by MGI curators] |