| Primary Identifier | MGI:2153463 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 140498 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-hormone receptor activity. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway and male gonad development. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; genitourinary system; and peritoneum. Used to study cryptorchidism. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human RXFP2 (relaxin family peptide receptor 2). PHENOTYPE: Male homozygotes for a targeted null mutation exhibit bilateral intraabdominal cryptorchidism and sterility associated with a failure in the differentiation of the gubernaculae, ligaments that control testicular movement during development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
