Primary Identifier | MGI:2140945 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 100710 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Acts upstream of or within lens development in camera-type eye. Predicted to be located in chromatin and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and sensory organ. Orthologous to human PDS5B (PDS5 cohesin associated factor B). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic and neonatal lethality with cardiac defects, craniofacial abnormalities, axial skeletal defects, shortening of most of the long bones, abnormal enteric nervous system morphology, and decreased germ cells. [provided by MGI curators] |