Primary Identifier | MGI:2385331 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 243362 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity. Acts upstream of or within negative regulation of sprouting angiogenesis. Predicted to be located in lipid droplet and mitochondrial membrane. Orthologous to human STARD13 (StAR related lipid transfer domain containing 13). PHENOTYPE: Mice homozygous for a knock-out allele exhibit small body size, decreased weight, and reduced adipose tissue. Mice homozygous for another knock-out allele exhibit increased angiogenesis in matrigel plugs and implanted tumors. [provided by MGI curators] |