| Primary Identifier | MGI:108543 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 21789 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in blood coagulation and cellular response to fluid shear stress. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including genitourinary system; liver; lung; small intestine; and spleen. Human ortholog(s) of this gene implicated in acute myeloid leukemia and retinal degeneration. Orthologous to human TFPI2 (tissue factor pathway inhibitor 2). PHENOTYPE: Mice homozygous for a null allele exhibit increased susceptibility to P. aeruginosa infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
