Primary Identifier | MGI:2157785 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 170676 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA binding activity. Involved in mRNA transport; protein homooligomerization; and vesicle-mediated intercellular transport. Acts upstream of or within placenta development. Located in cytoplasm. Is active in extracellular vesicle. Is expressed in several structures, including branchial arch; central nervous system; extraembryonic component; immune system; and reproductive system. Orthologous to human PEG10 (paternally expressed 10). PHENOTYPE: Heterozygous mice with a paternally inherited null allele display embryonic lethality during organogenesis with abnormal placental development. Heterozygous mice with a maternally inherited null allele are viable and fertile. [provided by MGI curators] |