| Primary Identifier | MGI:98474 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 21333 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable neurokinin receptor binding activity and receptor ligand activity. Acts upstream of or within several processes, including cellular response to nerve growth factor stimulus; response to pain; and sensory perception of pain. Located in axon; extracellular region; and neuronal cell body. Is expressed in several structures, including alimentary system; integumental system; limb; nervous system; and sensory organ. Orthologous to human TAC1 (tachykinin precursor 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit absence of agonist-induced hyperalgesia and an impaired response to chemical irritation of the urinary tract. Mice homozygous for a different knock-out allele display hypoalgesia, and reduced anxiety- and depression-related behaviors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
