| Primary Identifier | MGI:2443963 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 320405 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable lipid binding activity and metal ion binding activity. Involved in synaptic vesicle priming. Acts upstream of or within cellular response to starvation; hematopoietic stem cell homeostasis; and positive regulation of exocytosis. Located in cytoplasmic vesicle; postsynaptic membrane; and presynaptic membrane. Is active in glutamatergic synapse; parallel fiber to Purkinje cell synapse; and presynapse. Is expressed in several structures, including brain; genitourinary system; sensory organ; skeleton; and spinal cord. Used to study autism spectrum disorder. Orthologous to human CADPS2 (calcium dependent secretion activator 2). PHENOTYPE: Mice homozygous for a null allele exhibit defects in cerebellum, Purkinje cell and interneuron morphology, paired-pulse facilitation, and behaviors including emotional behavior, vestibuoocular reflex, circadium and sleep patterns, social investigation and nurturing behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
