| Primary Identifier | MGI:1920428 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 73178 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytoskeletal protein binding activity and identical protein binding activity. Involved in dendritic spine morphogenesis and regulation of postsynapse organization. Acts upstream of or within several processes, including actin cytoskeleton organization; response to bacterium; and spindle localization. Located in actin cap and lamellipodium. Is active in glutamatergic synapse. Is expressed in brain; genitourinary system; liver; and spleen. Used to study atopic dermatitis. Orthologous to human WASL (WASP like actin nucleation promoting factor). PHENOTYPE: Homozygous mutants exhibit developmental retardation, fail to undergo turning, show abnormal differentiation of intra- and extra-embryonal mesoderm, and die around midgestation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
