| Primary Identifier | MGI:1313297 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 14763 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables PDZ domain binding activity. Involved in cellular response to reactive oxygen species; dendrite development; and positive regulation of MAPK cascade. Acts upstream of or within dopamine biosynthetic process; locomotion involved in locomotory behavior; and positive regulation of dopamine metabolic process. Is active in cell surface and synapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human GPR37 (G protein-coupled receptor 37). PHENOTYPE: Mice homozygous for disruptions in this gene exhibit reduced striatal dopamine content, enhanced amphetamine sensitivity, reduced motor activity and coordination and increased percentage of body fat in females. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
