Primary Identifier | MGI:3629661 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 735266 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within cellular response to leukemia inhibitory factor. Is expressed in axial skeleton and cerebral cortex. Orthologous to human MIR592 (microRNA 592). PHENOTYPE: Homozygous null mice show partial perinatal lethality, with more males affected by lethality. Adults show reduced motor coordination, social interaction, and novel object curiosity, and increased grooming. Cortical neurogenesis is affected, with repressed intermediate progenitor cell to mature neuron transition. [provided by MGI curators] |