Primary Identifier | MGI:1918128 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 232664 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in acrosome assembly and single fertilization. Located in acrosomal membrane. Is expressed in cerebral cortex and retina. Orthologous to human CCDC136 (coiled-coil domain containing 136). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility, globozoospermia, asthenozoospermia, and decreased in vitro fertilization frequency. [provided by MGI curators] |