Primary Identifier | MGI:88478 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 109697 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process and response to cadmium ion. Predicted to be active in extracellular space. Is expressed in several structures, including foregut-midgut junction and ovary. Used to study pancreatitis. Orthologous to human CPA1 (carboxypeptidase A1). PHENOTYPE: Mice homozygous for a null allele exhibit a slight decreased in circulating amylase level. Mice homozygous for an amino acid substitution exhibit progressive, chronic pancreatitis. [provided by MGI curators] |