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Protein Coding Gene : Cpa1 carboxypeptidase A1, pancreatic

Primary Identifier  MGI:88478 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  109697
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process and response to cadmium ion. Predicted to be active in extracellular space. Is expressed in several structures, including foregut-midgut junction and ovary. Used to study pancreatitis. Orthologous to human CPA1 (carboxypeptidase A1).
PHENOTYPE: Mice homozygous for a null allele exhibit a slight decreased in circulating amylase level. Mice homozygous for an amino acid substitution exhibit progressive, chronic pancreatitis. [provided by MGI curators]
  • synonyms:
  • carboxypeptidase A1, pancreatic,
  • MGI:1913347,
  • 0910001L12Rik,
  • Cpa1,
  • RIKEN cDNA 0910001L12 gene,
  • MGD-MRK-2102

Features --> Cross References

Genome

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0 CDSs

0 Exons

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0 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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1 Driver For