| Primary Identifier | MGI:3577024 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 619665 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chromatin binding activity. Acts upstream of or within positive regulation of sphingolipid mediated signaling pathway and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including brain; genitourinary system; gut; respiratory system; and skin. Orthologous to human KLF14 (KLF transcription factor 14). PHENOTYPE: Mice homozygous for a null allele display genome instability and increased tumor incidence with age. Mice homozygous for a conditional allele knocked out in the liver exhibit decreased circulating HDL cholesterol levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
