| Primary Identifier | MGI:1921604 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 74354 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable guanylate kinase activity. Involved in axoneme assembly and spermatogenesis. Located in acrosomal vesicle and manchette. Is expressed in olfactory epithelium. Orthologous to human LRGUK (leucine rich repeats and guanylate kinase domain containing). PHENOTYPE: Mice homozygous for an ENU-induced hypomorphic allele exhibit male infertility associated with oligoasthenoteratospermia and defects in acrosome attachment, manchette structure and function, sperm head shaping, and sperm tail axoneme extension. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
