| Primary Identifier | MGI:88250 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 109624 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin binding activity and myosin binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to act upstream of or within regulation of smooth muscle contraction. Located in actin cap and membrane. Is expressed in several structures, including arch of aorta; heart; intestine smooth muscle circular layer; oocyte; and retina. Orthologous to human CALD1 (caldesmon 1). PHENOTYPE: Some homozygous mutant mice develop hernia and those that do, die within 5-7 hours after birth. Mice homozygous for a different targeted allele fail to develop. Mice heterozygous for this allele exhibit increased urinary bladder weight, smooth muscle bundles and non-voiding contractions. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
