Primary Identifier | MGI:1923473 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 76223 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metallocarboxypeptidase activity. Involved in protein side chain deglutamylation. Predicted to be located in cytosol. Predicted to be active in centriole and cytoplasm. Is expressed in brain; early embryo; genitourinary system; heart; and liver. Orthologous to human AGBL3 (AGBL carboxypeptidase 3). PHENOTYPE: Homozygous mice for a targeted allele are viable and fertile. Mice homozygous for a knock-out allele exhibit normal response to herpes simplex virus (HSV) and vaccinia virus (VACV) infection. [provided by MGI curators] |