Primary Identifier | MGI:107917 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 20899 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including activation of meiosis; cellular response to retinoic acid; and germ cell development. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including 2-cell stage embryo; ganglia; gonad; mesonephros; and spleen primordium. Orthologous to human STRA8 (stimulated by retinoic acid 8). PHENOTYPE: Homozygous knockout affects meiosis during spermatogenesis and results in male sterility. [provided by MGI curators] |