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Protein Coding Gene : Cnot4 CCR4-NOT transcription complex, subunit 4

Primary Identifier  MGI:1859026 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  53621
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein autoubiquitination; regulation of megakaryocyte differentiation; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be part of CCR4-NOT complex. Is expressed in several structures, including central nervous system; genitourinary system; neural retina; and olfactory epithelium. Orthologous to human CNOT4 (CCR4-NOT transcription complex subunit 4).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal placental and chorion formation and complete lethality throughout fetal growth and development. [provided by MGI curators]
  • synonyms:
  • CCR4-NOT transcription complex, subunit 4,
  • Not4hp,
  • negative regulator of transcription 4 homolog (S. cerevisiae),
  • Cnot4,
  • Not4,
  • Not4h

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For