Primary Identifier | MGI:1859026 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 53621 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein autoubiquitination; regulation of megakaryocyte differentiation; and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol. Predicted to be part of CCR4-NOT complex. Is expressed in several structures, including central nervous system; genitourinary system; neural retina; and olfactory epithelium. Orthologous to human CNOT4 (CCR4-NOT transcription complex subunit 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal placental and chorion formation and complete lethality throughout fetal growth and development. [provided by MGI curators] |