Primary Identifier | MGI:1913367 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 66117 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including dopaminergic neuron differentiation; motor behavior; and regulation of type B pancreatic cell proliferation. Located in mitochondrion. Is expressed in several structures, including adrenal gland; brain; gut gland; male reproductive gland or organ; and trachea. Orthologous to several human genes including FMC1 (formation of mitochondrial complex V assembly factor 1 homolog). PHENOTYPE: Mice homozygous for a null allele exhibit postnatal lethality. Mice heterozygous for a null allele exhibit resistance to MPTP-induced parkinsonism. [provided by MGI curators] |