| Primary Identifier | MGI:98497 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 21391 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables thromboxane-A synthase activity. Predicted to be involved in intracellular chloride ion homeostasis; positive regulation of vasoconstriction; and prostaglandin biosynthetic process. Predicted to be located in cytosol and endoplasmic reticulum membrane. Is expressed in several structures, including bone marrow; brain; liver; lung; and metanephros. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome and cerebral infarction. Orthologous to human TBXAS1 (thromboxane A synthase 1). PHENOTYPE: Homozygous null mice display increased bleeding time and decreased platelet response to arachidonic acid. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
