Primary Identifier | MGI:3027899 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 381759 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein tyrosine kinase activity. Involved in several processes, including female pronucleus assembly; negative regulation of oocyte maturation; and regulation of phosphorylation. Located in cytoplasm and nucleus. Is expressed in early embryo; olfactory epithelium; and ovary. Orthologous to human WEE2 (WEE2 oocyte meiosis inhibiting kinase). PHENOTYPE: Mice homozygous for a short deletion exhibit normal female fertility. Mice homozygous for a large deletion exhibit reduced litter size from female mice without any other changes in reproductive parameters. [provided by MGI curators] |