| Primary Identifier | MGI:1914940 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 67690 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity and serine-type endopeptidase activity. Involved in positive regulation of fertilization. Acts upstream of or within binding activity of sperm to zona pellucida; germ cell migration; and protein maturation. Predicted to be located in extracellular region. Predicted to be active in acrosomal vesicle and extracellular space. Orthologous to human PRSS37 (serine protease 37). PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility associated with impaired zona binding and migration from the uterus into the oviduct. [provided by MGI curators] |