Primary Identifier | MGI:98587 | Organism | mouse, laboratory |
Chromosome | 6 | Mgi Type | gene segment |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human TRBV11-1 (T cell receptor beta variable 11-1); TRBV11-2 (T cell receptor beta variable 11-2); and TRBV11-3 (T cell receptor beta variable 11-3). PHENOTYPE: Mice homozygous for either of two knock-out alleles exhibit decreased T cell number with virtually no production of Vbeta13-expressing T cells. [provided by MGI curators] |