Primary Identifier | MGI:1096338 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 13848 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transmembrane-ephrin receptor activity. Acts upstream of or within activated T cell proliferation; positive regulation of T cell costimulation; and type IV hypersensitivity. Located in cell surface. Is expressed in several structures, including alimentary system; integumental system; intraembryonic coelom; nervous system; and sensory organ. Orthologous to human EPHB6 (EPH receptor B6). PHENOTYPE: T cell responses such as lymphokine secretion, proliferation, and the development of delayed-type skin hypersensitivity and experimental autoimmune encephalitis were compromised in homozygous null mutants. [provided by MGI curators] |