| Primary Identifier | MGI:1927259 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 64177 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium channel activity and identical protein binding activity. Involved in calcium ion homeostasis; calcium ion import across plasma membrane; and response to calcium ion. Acts upstream of or within calcium ion transport and parathyroid hormone secretion. Part of calcium channel complex. Is expressed in several structures, including central nervous system; gut; placenta; sensory organ; and submandibular gland primordium. Human ortholog(s) of this gene implicated in hyperparathyroidism. Orthologous to human TRPV6 (transient receptor potential cation channel subfamily V member 6). PHENOTYPE: Mice homozygous for a knock-in allele exhibit impaired sperm motility and decreased fertilization by sperm. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
