| Primary Identifier | MGI:106340 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 217864 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables chromatin binding activity; enzyme binding activity; and transcription corepressor activity. Involved in negative regulation of gene expression and positive regulation of megakaryocyte differentiation. Acts upstream of or within erythrocyte differentiation. Predicted to be located in nucleoplasm. Predicted to be part of DNA repair complex; nucleoplasm; and transcription repressor complex. Is expressed in several structures, including brain; early embryo; liver; nose; and testis. Orthologous to human RCOR1 (REST corepressor 1). PHENOTYPE: Mice homozygous for a null allele exhibit partial embryonic lethality, defective embryonic erythropoiesis, and decreased erythroid progenitor cell number. No homozygotes survive to P7. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
