| Primary Identifier | MGI:1349658 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 26965 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin ligase complex scaffold activity and ubiquitin protein ligase binding activity. Predicted to contribute to ubiquitin protein ligase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including apoptotic process; cell population proliferation; and protein ubiquitination. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including adrenal gland; genitourinary system; immune system; neural retina; and telencephalon. Orthologous to human CUL1 (cullin 1). PHENOTYPE: Homozygotes for targeted null mutations accumulate cyclin E1 and exhibit arrested development and lethality around embryonic day 6.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
