Primary Identifier | MGI:1916478 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 69228 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ubiquitin protein ligase binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Is expressed in central nervous system; genitourinary system; and lung epithelium. Orthologous to several human genes including ZNF746 (zinc finger protein 746). PHENOTYPE: Mice homozygous for a null allele show decreased incidence of DEN-induced liver tumors. [provided by MGI curators] |