Primary Identifier | MGI:1918910 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 71660 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable signaling receptor binding activity. Involved in several processes, including positive regulation of fat cell differentiation; regulation of insulin receptor signaling pathway; and regulation of primary metabolic process. Acts upstream of or within brown fat cell differentiation. Located in extracellular region. Is expressed in genitourinary system; jaw; and retina. Orthologous to human RARRES2 (retinoic acid receptor responder 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired glucose tolerance, impaired glucose-stimulated insulin secretion and increased clamp hepatic glucose production. [provided by MGI curators] |