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Protein Coding Gene : Gimap1 GTPase, IMAP family member 1
Primary Identifier  MGI:109368 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  16205
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables GTP binding activity. Acts upstream of or within B cell differentiation; CD4-positive, alpha-beta T cell differentiation; and CD8-positive, alpha-beta T cell differentiation. Located in endoplasmic reticulum. Orthologous to human GIMAP1 (GTPase, IMAP family member 1).
PHENOTYPE: Mice homozygous for a null allele have defects in the development of mature B and T lymphocytes. [provided by MGI curators]
  • synonyms:
  • imap,
  • IAP38,
  • MGD-MRK-38413,
  • 38kDa,
  • Gimap1,
  • GTPase, IMAP family member 1,
  • immunity-associated protein,
  • Imap38
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