| Primary Identifier | MGI:1932723 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 83408 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTP binding activity. Acts upstream of or within mitochondrial genome maintenance. Located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in portal hypertension. Orthologous to several human genes including GIMAP5 (GTPase, IMAP family member 5). PHENOTYPE: Homozygous KO reduces competitiveness of T cells with wild-type in spleen and thymus in a chimeric bone marrow transplantation model. KO in conjunction with Gimap5 KO exacerbates the reduction in T cell numbers in spleen and lymph nodes of Gimap5 single-KO. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
