| Primary Identifier | MGI:1927138 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 56349 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables small GTPase binding activity. Acts upstream of or within myoblast migration and positive regulation of substrate adhesion-dependent cell spreading. Located in nucleus and plasma membrane. Is expressed in forelimb bud and submandibular gland primordium epithelium. Orthologous to human NET1 (neuroepithelial cell transforming 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit delayed mammary gland development during puberty associated with slower ductal extension, reduced ductal branching and epithelial cell proliferation, disorganized myoepithelial and ductal epithelial cells, and increased collagen deposition. [provided by MGI curators] |