Primary Identifier | MGI:2141450 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 231986 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity. Predicted to be involved in lipid metabolic process. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; limb bud; limb interdigital region mesenchyme; nervous system; and reproductive system. Orthologous to human JAZF1 (JAZF zinc finger 1). PHENOTYPE: Homozygous knockout in pancreatic beta cells affects protein synthesis and reduces beta cell proliferation. [provided by MGI curators] |