Primary Identifier | MGI:2443973 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 231991 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in white fat cell differentiation. Acts upstream of or within adipose tissue development; fat cell differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including limb; neural tube; oral epithelium; palatal shelf; and telencephalon ventricular layer. Orthologous to human CREB5 (cAMP responsive element binding protein 5). PHENOTYPE: Mice homozygous for a null mutation display neonatal lethality. [provided by MGI curators] |