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Protein Coding Gene : Ggct gamma-glutamyl cyclotransferase
Primary Identifier  MGI:95700 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  110175
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable gamma-glutamylcyclotransferase activity and protein homodimerization activity. Predicted to be involved in release of cytochrome c from mitochondria. Predicted to be located in cytosol. Is expressed in lens. Orthologous to human GGCT (gamma-glutamylcyclotransferase).
PHENOTYPE: Mice homozygous for a null allele exhibit splenomegaly and progressive anemia associated with oxidative stress and reduced red blood cell life span. [provided by MGI curators]
  • synonyms:
  • EST AA673177,
  • AA673177,
  • Ggc,
  • Ggct,
  • MGI:1915502,
  • A030007L17Rik,
  • gamma-glutamyl cyclotransferase,
  • RIKEN cDNA A030007L17 gene,
  • MGD-MRK-10058,
  • MGI:1889375,
  • Gctg
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Phenotype

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Disease

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