Primary Identifier | MGI:103201 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 11826 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ephrin receptor binding activity; potassium ion transmembrane transporter activity; and water transmembrane transporter activity. Involved in several processes, including defense response to Gram-negative bacterium; lateral ventricle development; and metanephros development. Acts upstream of or within several processes, including corticotropin secretion; glomerular filtration; and renal water absorption. Located in several cellular components, including basolateral plasma membrane; brush border; and extracellular exosome. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; sensory organ; and skeleton. Orthologous to human AQP1 (aquaporin 1 (Colton blood group)). PHENOTYPE: Homozygous mutation of this gene results in urine hypoosmality. [provided by MGI curators] |