| Primary Identifier | MGI:2384811 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 210973 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Acts upstream of or within with a positive effect on several processes, including glucose metabolic process; phosphatidylinositol 3-kinase/protein kinase B signal transduction; and response to insulin. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human KBTBD2 (kelch repeat and BTB domain containing 2). PHENOTYPE: Mice homozygous for a knock-out allele or mutation exhibit diabetes, lipodystrophy, and hepatic steatosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
