| Primary Identifier | MGI:1918195 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 70945 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity. Predicted to be an extracellular matrix structural constituent. Involved in negative regulation of wound healing and positive regulation of platelet aggregation. Located in collagen-containing extracellular matrix. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; genitourinary system; hemolymphoid system gland; and meninges. Orthologous to human MMRN1 (multimerin 1). PHENOTYPE: Mice homozygous for a null allele exhibit decreased susceptibility to thrombus formation in the ferric chloride injury model, impaired platelet adhesion to GPAGPOGPX peptides and fibrillar collagen, and a reduced size of platelet aggregates captured onto collagen, triple-helical collagen mimetic peptides, von Willebrand factor, and fibrinogen. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
