| Primary Identifier | MGI:1927344 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 57441 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables DNA-binding transcription factor binding activity and transcription corepressor activity. Involved in several processes, including negative regulation of DNA replication; negative regulation of DNA-templated transcription; and negative regulation of cell cycle. Acts upstream of or within animal organ morphogenesis. Located in nucleus. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 6. Orthologous to human GMNN (geminin DNA replication inhibitor). PHENOTYPE: Homozygotes for targeted null mutations exhibit early embryonic lethality, defective inner cell mass formation, and endoreduplication. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
