Primary Identifier | MGI:1918343 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 71093 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity and DNA-binding transcription factor binding activity. Involved in formation of primary germ layer; myoblast proliferation; and negative regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; heart and pericardium; and respiratory system. Orthologous to human ATOH8 (atonal bHLH transcription factor 8). PHENOTYPE: Mice homozygous for a knock-in allele appear to be developmentally arrested at or slightly after gastrulation. [provided by MGI curators] |