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Protein Coding Gene : Sftpb surfactant associated protein B

Primary Identifier  MGI:109516 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  20388
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be involved in respiratory gaseous exchange by respiratory system and sphingolipid metabolic process. Located in cytoplasm. Is expressed in lung surfactant and respiratory system. Human ortholog(s) of this gene implicated in lung disease (multiple); respiratory syncytial virus infectious disease; and toxic shock syndrome. Orthologous to human SFTPB (surfactant protein B).
PHENOTYPE: Inactivation of this gene results in respiratory failure. [provided by MGI curators]
  • synonyms:
  • AI562151,
  • MGD-MRK-14382,
  • surfactant-associated protein 3,
  • surfactant associated protein B,
  • Sftpb,
  • MGD-MRK-14379,
  • SP-B,
  • expressed sequence AI562151,
  • MGD-MRK-39515,
  • MGI:2141447,
  • Sftp3,
  • SF-B,
  • Sftp-3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For