| Primary Identifier | MGI:1098259 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 12332 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and protein domain specific binding activity. Acts upstream of or within cell projection assembly and cellular response to type II interferon. Located in phagocytic vesicle. Is expressed in several structures, including central nervous system; epithelium; forelimb; jaw; and metanephros. Orthologous to human CAPG (capping actin protein, gelsolin like). PHENOTYPE: Inactivation of this loci results in impaired immune cell motility which manifests in homozygous mutant mice as increased susceptibility to some bacterial infections. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
