Primary Identifier | MGI:1914692 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 67442 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables all-trans-retinol 13,14-reductase activity. Involved in retinol metabolic process. Located in endoplasmic reticulum membrane and nuclear outer membrane. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human RETSAT (retinol saturase). PHENOTYPE: Mice homozygous for a knock-out allele are deficient in the production of all-trans-13,14-dihydroretinol from dietary vitamin A and exhibit increased adiposity. [provided by MGI curators] |